Frank Herzberg has appeared on nearly 60 CD's as a bassist, plays regularly with his own trio, and with the Marta Karassawa Quintet, John Stein Group, and the André Juarez Quartet, among others. He works also as a studio musician and producer for instrumental music in Brazil. He appears regularly at festivals giving concerts and workshops about improvisation.

During his carrier he has appeared on stage, in the studio, or in workshops with Horace Sliver, Antonio Sanchez, John Stein, Zé Eduardo Nazário, Ithamara Koorax, Bocato, Guilherme Franco, Teco Cardoso, André Juarez, Torsten de Winkel, Bob Moses, Jaques Schwartzbart, Steve Hass, Cornelius Claudio Kreusch, Andre Pawelski, and Chris Allen, among others.

Frank Herzberg works as a acoustic bassist in various orchestras in Brazil, including the Symphonic Band/São Paulo, Jazzsinfonic Orchester/São Paulo, and Orquestra Mediterrânia, where he has accompanied well-known musicians like David Liebman, Hermeto Pascoal, Egberto Gismonti, Ginga, and Airto Moreira, among others.